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Mammalian Glycosylation Patterns Protect Citrullinated Chemokine MCP-1/CCL2 from Partial Degradation

Monocyte chemoattractant protein-1 (MCP-1/CCL2) is a potent chemotactic agent for monocytes, primarily produced by macrophages and endothelial cells. Significantly elevated levels of MCP-1/CCL2 were found in synovial fluids of patients with rheumatoid arthritis (RA), compared to osteoarthritis or ot...

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Detalles Bibliográficos
Autores principales: Korchynskyi, Olexandr, Yoshida, Ken, Korchynska, Nataliia, Czarnik-Kwaśniak, Justyna, Tak, Paul P., Pruijn, Ger J. M., Isozaki, Takeo, Ruth, Jeffrey H., Campbell, Phillip L., Amin, M. Asif, Koch, Alisa E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915159/
https://www.ncbi.nlm.nih.gov/pubmed/36768186
http://dx.doi.org/10.3390/ijms24031862