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Organogermanium THGP Induces Differentiation into M1 Macrophages and Suppresses the Proliferation of Melanoma Cells via Phagocytosis

M1 macrophages are an important cell type related to tumor immunology and are known to phagocytose cancer cells. In previous studies, the organogermanium compound poly-trans-[(2-carboxyethyl)germasesquioxane] (Ge-132) and its hydrolysate, 3-(trihydroxygermyl) propanoic acid (THGP), have been reporte...

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Detalles Bibliográficos
Autores principales: Azumi, Junya, Takeda, Tomoya, Shimada, Yasuhiro, Zhuang, Tao, Tokuji, Yoshihiko, Sakamoto, Naoya, Aso, Hisashi, Nakamura, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915250/
https://www.ncbi.nlm.nih.gov/pubmed/36768216
http://dx.doi.org/10.3390/ijms24031885