Antitumor Effect of Korean Red Ginseng through Blockade of PD-1/PD-L1 Interaction in a Humanized PD-L1 Knock-In MC38 Cancer Mouse Model

Blocking immune checkpoints, programmed death-1 (PD-1) and its ligand PD-L1, has proven a promising anticancer strategy for enhancing cytotoxic T cell activity. Although we previously demonstrated that ginsenoside Rg3, Rh2, and compound K block the interaction of PD-1 and PD-L1, the antitumor effect...

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Detalles Bibliográficos
Autores principales: Lee, Eun-Ji, Yang, Ju-Hye, Yang, Hye Jin, Cho, Chong-Kwan, Choi, Jang-Gi, Chung, Hwan-Suck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915403/
https://www.ncbi.nlm.nih.gov/pubmed/36768213
http://dx.doi.org/10.3390/ijms24031894

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915403/
https://www.ncbi.nlm.nih.gov/pubmed/36768213
http://dx.doi.org/10.3390/ijms24031894

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