m(6)A RNA methylation orchestrates transcriptional dormancy during developmental pausing

Embryos across metazoan lineages can enter reversible states of developmental pausing, or diapause, in response to adverse environmental conditions. The molecular mechanisms that underlie this remarkable dormant state remain largely unknown. Here we show that m(6)A RNA methylation by Mettl3 is requi...

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Detalles Bibliográficos
Autores principales: Collignon, Evelyne, Cho, Brandon, Fothergill-Robinson, Julie, Furlan, Giacomo, Ross, Robert L., Limbach, Patrick A., Ramalho-Santos, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915470/
https://www.ncbi.nlm.nih.gov/pubmed/36778216
http://dx.doi.org/10.1101/2023.01.30.526234

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915470/
https://www.ncbi.nlm.nih.gov/pubmed/36778216
http://dx.doi.org/10.1101/2023.01.30.526234

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