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m(6)A RNA methylation orchestrates transcriptional dormancy during developmental pausing
Embryos across metazoan lineages can enter reversible states of developmental pausing, or diapause, in response to adverse environmental conditions. The molecular mechanisms that underlie this remarkable dormant state remain largely unknown. Here we show that m(6)A RNA methylation by Mettl3 is requi...
Autores principales: | Collignon, Evelyne, Cho, Brandon, Fothergill-Robinson, Julie, Furlan, Giacomo, Ross, Robert L., Limbach, Patrick A., Ramalho-Santos, Miguel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915470/ https://www.ncbi.nlm.nih.gov/pubmed/36778216 http://dx.doi.org/10.1101/2023.01.30.526234 |
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