Influenza A virus modulation of Streptococcus pneumoniae infection using ex vivo transcriptomics in a human primary lung epithelial cell model reveals differential host glycoconjugate uptake and metabolism

BACKGROUND: Streptococcus pneumoniae (Spn) is typically an asymptomatic colonizer of the nasopharynx but it also causes pneumonia and disseminated disease affecting various host anatomical sites. Transition from colonization to invasive disease is not well understood. Studies have shown that such a...

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Detalles Bibliográficos
Autores principales: D’Mello, Adonis, Lane, Jessica R, Tipper, Jennifer L, Martínez, Eriel, Roussey, Holly N, Harrod, Kevin S, Orihuela, Carlos J, Tettelin, Hervé
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915477/
https://www.ncbi.nlm.nih.gov/pubmed/36778321
http://dx.doi.org/10.1101/2023.01.29.526157

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915477/
https://www.ncbi.nlm.nih.gov/pubmed/36778321
http://dx.doi.org/10.1101/2023.01.29.526157

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