Lumbar endplate microfracture injury induces Modic-like changes, intervertebral disc degeneration and spinal cord sensitization – An In Vivo Rat Model

BACKGROUND CONTEXT: Endplate (EP) injury plays critical roles in painful IVD degeneration since Modic changes (MCs) are highly associated with pain. Models of EP microfracture that progress to painful conditions are needed to better understand pathophysiological mechanisms and screen therapeutics. P...

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Detalles Bibliográficos
Autores principales: Wang, Dalin, Lai, Alon, Gansau, Jennifer, Seifert, Alan C., Munitz, Jazz, Zaheer, Kashaf, Bhadouria, Neharika, Lee, Yunsoo, Nasser, Philip, Laudier, Damien M., Holguin, Nilsson, Hecht, Andrew C., Iatridis, James C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915494/
https://www.ncbi.nlm.nih.gov/pubmed/36778423
http://dx.doi.org/10.1101/2023.01.27.525924

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915494/
https://www.ncbi.nlm.nih.gov/pubmed/36778423
http://dx.doi.org/10.1101/2023.01.27.525924

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