Cargando…
Lumbar endplate microfracture injury induces Modic-like changes, intervertebral disc degeneration and spinal cord sensitization – An In Vivo Rat Model
BACKGROUND CONTEXT: Endplate (EP) injury plays critical roles in painful IVD degeneration since Modic changes (MCs) are highly associated with pain. Models of EP microfracture that progress to painful conditions are needed to better understand pathophysiological mechanisms and screen therapeutics. P...
Autores principales: | Wang, Dalin, Lai, Alon, Gansau, Jennifer, Seifert, Alan C., Munitz, Jazz, Zaheer, Kashaf, Bhadouria, Neharika, Lee, Yunsoo, Nasser, Philip, Laudier, Damien M., Holguin, Nilsson, Hecht, Andrew C., Iatridis, James C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915494/ https://www.ncbi.nlm.nih.gov/pubmed/36778423 http://dx.doi.org/10.1101/2023.01.27.525924 |
Ejemplares similares
-
Spinal Cord Sensitization and Spinal Inflammation from an In Vivo Rat Endplate Injury Associated with Painful Intervertebral Disc Degeneration
por: Lai, Alon, et al.
Publicado: (2023) -
Raloxifene Stimulates Estrogen Signaling to Protect Against Age- and Sex-Related Intervertebral Disc Degeneration in Mice
por: Bhadouria, Neharika, et al.
Publicado: (2022) -
Spatial mapping of collagen content and structure in human intervertebral disk degeneration
por: Zeldin, Lawrence, et al.
Publicado: (2020) -
Suppression of Sost/Sclerostin and Dickkopf‐1 Augment Intervertebral Disc Structure in Mice
por: Kroon, Tori, et al.
Publicado: (2022) -
Lubricin expression in the lumbar endplate and its association with Modic changes
por: Liu, Junhui, et al.
Publicado: (2019)