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Production of antigenically stable enterovirus A71 virus-like particles in Pichia pastoris as a vaccine candidate

Enterovirus A71 (EVA71) causes widespread disease in young children with occasional fatal consequences. In common with other picornaviruses, both empty capsids (ECs) and infectious virions are produced during the viral lifecycle. While initially antigenically indistinguishable from virions, ECs read...

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Detalles Bibliográficos
Autores principales: Kingston, Natalie J, Snowden, Joseph S, Martyna, Agnieszka, Shegdar, Mona, Grehan, Keith, Tedcastle, Alison, Pegg, Elaine, Fox, Helen, Macadam, Andrew J, Martin, Javier, Hogle, James M, Rowlands, David J, Stonehouse, Nicola J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915507/
https://www.ncbi.nlm.nih.gov/pubmed/36778240
http://dx.doi.org/10.1101/2023.01.30.526315