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Production of antigenically stable enterovirus A71 virus-like particles in Pichia pastoris as a vaccine candidate
Enterovirus A71 (EVA71) causes widespread disease in young children with occasional fatal consequences. In common with other picornaviruses, both empty capsids (ECs) and infectious virions are produced during the viral lifecycle. While initially antigenically indistinguishable from virions, ECs read...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915507/ https://www.ncbi.nlm.nih.gov/pubmed/36778240 http://dx.doi.org/10.1101/2023.01.30.526315 |