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Glucose deprivation promotes pseudo-hypoxia and de-differentiation in lung adenocarcinoma

Increased utilization of glucose is a hallmark of cancer. Several studies are investigating the efficacy of glucose restriction by glucose transporter blockade or glycolysis inhibition. However, the adaptations of cancer cells to glucose restriction are unknown. Here, we report the discovery that gl...

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Detalles Bibliográficos
Autores principales: Saggese, Pasquale, Pandey, Aparamita, Fung, Eileen, Hall, Abbie, Yanagawa, Jane, Rodriguez, Erika F., Grogan, Tristan R., Giurato, Giorgio, Nassa, Giovanni, Salvati, Annamaria, Weisz, Alessandro, Dubinett, Steven M., Scafoglio, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915520/
https://www.ncbi.nlm.nih.gov/pubmed/36778362
http://dx.doi.org/10.1101/2023.01.30.526207