Arsenic: A Perspective on Its Effect on Pioglitazone Bioavailability

Arsenic (As) is a common contaminant in drinking water in northeastern Mexico, which reduces the expression of cytochrome P450 (CYP 450). This enzyme group metabolizes numerous drugs, such as oral antidiabetic drugs such as pioglitazone (61% CYP 3A4, 49% CYP 2C8). When CYP 450’s function is inadequa...

Descripción completa

Detalles Bibliográficos
Autores principales: Terrones-Gurrola, María Cruz del Rocío, Ponce-Peña, Patricia, Salas-Pacheco, José Manuel, Camacho-Luis, Abelardo, Pozos-Guillén, Amaury de Jesús, Nieto-Delgado, Guillermo, López-Guzmán, Olga Dania, Vértiz-Hernández, Angel Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915544/
https://www.ncbi.nlm.nih.gov/pubmed/36767268
http://dx.doi.org/10.3390/ijerph20031901

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915544/
https://www.ncbi.nlm.nih.gov/pubmed/36767268
http://dx.doi.org/10.3390/ijerph20031901

Ejemplares similares