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Frequency variation and dose modification of benznidazole administration for the treatment of Trypanosoma cruzi infection in mice, dogs and non-human primates

Trypanosoma cruzi naturally infects a broad range of mammalian species and frequently results in the pathology that has been most extensively characterized in human Chagas disease. Currently employed treatment regimens fail to achieve parasitological cure of T. cruzi infection in the majority of cas...

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Detalles Bibliográficos
Autores principales: Bustamante, Juan M., White, Brooke E., Wilkerson, Gregory K., Hodo, Carolyn L., Auckland, Lisa D., Wang, Wei, McCain, Stephanie, Hamer, Sarah A., Saunders, Ashley B., Tarleton, Rick L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915573/
https://www.ncbi.nlm.nih.gov/pubmed/36778432
http://dx.doi.org/10.1101/2023.02.01.526739