Cargando…

Frequency variation and dose modification of benznidazole administration for the treatment of Trypanosoma cruzi infection in mice, dogs and non-human primates

Trypanosoma cruzi naturally infects a broad range of mammalian species and frequently results in the pathology that has been most extensively characterized in human Chagas disease. Currently employed treatment regimens fail to achieve parasitological cure of T. cruzi infection in the majority of cas...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bustamante, Juan M., White, Brooke E., Wilkerson, Gregory K., Hodo, Carolyn L., Auckland, Lisa D., Wang, Wei, McCain, Stephanie, Hamer, Sarah A., Saunders, Ashley B., Tarleton, Rick L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915573/ https://www.ncbi.nlm.nih.gov/pubmed/36778432 http://dx.doi.org/10.1101/2023.02.01.526739

Ejemplares similares

Prophylactic low-dose, bi-weekly benznidazole treatment fails to prevent Trypanosoma cruzi infection in dogs under intense transmission pressure
por: Bustamante, Juan M., et al.
Publicado: (2022)

Trypanosoma cruzi Transmission Among Captive Nonhuman Primates, Wildlife, and Vectors
por: Hodo, Carolyn L., et al.
Publicado: (2018)

Trypanosoma cruzi infections and associated pathology in urban-dwelling Virginia opossums (Didelphis virginiana)
por: Zecca, Italo B., et al.
Publicado: (2020)

High incidence of Trypanosoma cruzi infections in dogs directly detected through longitudinal tracking at 10 multi-dog kennels, Texas, USA
por: Busselman, Rachel E., et al.
Publicado: (2021)

Benznidazole Biotransformation and Multiple Targets in Trypanosoma cruzi Revealed by Metabolomics
por: Trochine, Andrea, et al.
Publicado: (2014)

Transcriptomic analysis of benznidazole-resistant and susceptible Trypanosoma cruzi populations
por: Lima, Davi Alvarenga, et al.
Publicado: (2023)

Reaching for the Holy Grail: insights from infection/cure models on the prospects for vaccines for Trypanosoma cruzi infection
por: Bustamante, Juan, et al.
Publicado: (2015)

Nanocarrier-enhanced intracellular delivery of benznidazole for treatment of Trypanosoma cruzi infection
por: Li, Xiaomo, et al.
Publicado: (2021)

Toward an Ecological Framework for Assessing Reservoirs of Vector-Borne Pathogens: Wildlife Reservoirs of Trypanosoma cruzi across the Southern United States
por: Hodo, Carolyn L, et al.
Publicado: (2017)

Combined Treatment of Heterocyclic Analogues and Benznidazole upon Trypanosoma cruzi In Vivo
por: Batista, Denise da Gama Jaén, et al.
Publicado: (2011)

Benznidazole Treatment: Time- and Dose-Dependence Varies with the Trypanosoma cruzi Strain
por: Fonseca, Kátia da Silva, et al.
Publicado: (2021)

Benznidazole-resistance in Trypanosoma cruzi: Evidence that distinct mechanisms can act in concert()
por: Campos, Mônica C.O., et al.
Publicado: (2014)

Chromosome level assembly of the hybrid Trypanosoma cruzi genome
por: Weatherly, D Brent, et al.
Publicado: (2009)

Nationwide Exposure of U.S. Working Dogs to the Chagas Disease Parasite, Trypanosoma cruzi
por: Meyers, Alyssa C., et al.
Publicado: (2020)

Drug transporter and oxidative stress gene expression in human macrophages infected with benznidazole-sensitive and naturally benznidazole-resistant Trypanosoma cruzi parasites treated with benznidazole
por: Téllez, Jair, et al.
Publicado: (2019)

Miltefosine and Benznidazole Combination Improve Anti-Trypanosoma cruzi In Vitro and In Vivo Efficacy
por: Gulin, Julián Ernesto Nicolás, et al.
Publicado: (2022)

Effect of benznidazole on cerebral microcirculation during acute Trypanosoma cruzi infection in mice
por: Gonzaga, Beatriz Matheus Souza, et al.
Publicado: (2022)

Molecular characterization of the hexose transporter gene in benznidazole resistant and susceptible populations of Trypanosoma cruzi
por: dos Santos, Paula F, et al.
Publicado: (2012)

Repeated cross‐sectional study of Trypanosoma cruzi in shelter dogs in Texas, in the context of Dirofilaria immitis and tick‐borne pathogen prevalence
por: Hodo, Carolyn L., et al.
Publicado: (2018)

Selected cardiac abnormalities in Trypanosoma cruzi serologically positive, discordant, and negative working dogs along the Texas-Mexico border
por: Meyers, Alyssa C., et al.
Publicado: (2020)

Trypanosome species, including Trypanosoma cruzi, in sylvatic and peridomestic bats of Texas, USA
por: Hodo, Carolyn L., et al.
Publicado: (2016)

Evaluation of high efficiency gene knockout strategies for Trypanosoma cruzi
por: Xu, Dan, et al.
Publicado: (2009)

A novel ABCG-like transporter of Trypanosoma cruzi is involved in natural resistance to benznidazole
por: Zingales, Bianca, et al.
Publicado: (2015)

Looking for combination of benznidazole and Trypanosoma cruzi-triosephosphate isomerase inhibitors for Chagas disease treatment
por: Aguilera, Elena, et al.
Publicado: (2018)

Anti-parasitic effect of vitamin C alone and in combination with benznidazole against Trypanosoma cruzi
por: Puente, Vanesa, et al.
Publicado: (2018)

Recombination-driven generation of the largest pathogen repository of antigen variants in the protozoan Trypanosoma cruzi
por: Weatherly, D. Brent, et al.
Publicado: (2016)

Benznidazole/Itraconazole Combination Treatment Enhances Anti-Trypanosoma cruzi Activity in Experimental Chagas Disease
por: Assíria Fontes Martins, Tassiane, et al.
Publicado: (2015)

Benznidazole and amiodarone combined treatment attenuates cytoskeletal damage in Trypanosoma cruzi-infected cardiac cells
por: Barbosa, Juliana Magalhães Chaves, et al.
Publicado: (2022)

Antiparasitic Activity of Hippeastrum Species and Synergistic Interaction between Montanine and Benznidazole against Trypanosoma cruzi
por: Piñeiro, Mauricio, et al.
Publicado: (2023)

Spontaneous dormancy protects Trypanosoma cruzi during extended drug exposure
por: Sánchez-Valdéz, Fernando J, et al.
Publicado: (2018)

In Vitro and In Vivo High-Throughput Assays for the Testing of Anti-Trypanosoma cruzi Compounds
por: Canavaci, Adriana M. C., et al.
Publicado: (2010)

Electrocardiographic Abnormalities and Treatment with Benznidazole among Children with Chronic Infection by Trypanosoma cruzi: A Retrospective Cohort Study
por: Colantonio, Lisandro D., et al.
Publicado: (2016)

Strain-specific genome evolution in Trypanosoma cruzi, the agent of Chagas disease
por: Wang, Wei, et al.
Publicado: (2021)

The steady-state transcriptome of the four major life-cycle stages of Trypanosoma cruzi
por: Minning, Todd A, et al.
Publicado: (2009)

A Quinoxaline Derivative as a Potent Chemotherapeutic Agent, Alone or in Combination with Benznidazole, against Trypanosoma cruzi
por: Rodrigues, Jean Henrique da Silva, et al.
Publicado: (2014)

Cardiac diagnostic test results and outcomes in 44 dogs naturally infected with Trypanosoma cruzi
por: Matthews, Derek J., et al.
Publicado: (2021)

Benznidazole Therapy Modulates Interferon-γ and M2 Muscarinic Receptor Autoantibody Responses in Trypanosoma cruzi-Infected Children
por: Cutrullis, Romina A., et al.
Publicado: (2011)

Cardiac Manifestations of Trypanosoma cruzi Infection in a Domestic Dog
por: Stoner, Caitlin H., et al.
Publicado: (2020)

CRISPR-Cas9-Mediated Single-Gene and Gene Family Disruption in Trypanosoma cruzi
por: Peng, Duo, et al.
Publicado: (2014)

Shelter Dogs as Sentinels for Trypanosoma cruzi Transmission across Texas
por: Tenney, Trevor D., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_6sg0vi9cu50sg1jp61kt8e7v8v