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RGS14 is neuroprotective against seizure-induced mitochondrial oxidative stress and pathology in hippocampus

RGS14 is a complex multifunctional scaffolding protein that is highly enriched within pyramidal cells (PCs) of hippocampal area CA2. There, RGS14 suppresses glutamate-induced calcium influx and related G protein and ERK signaling in dendritic spines to restrain postsynaptic signaling and plasticity....

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Detalles Bibliográficos
Autores principales: Harbin, Nicholas H, Lustberg, Daniel J, Hurst, Cheyenne, Pare, Jean-Francois, Crotty, Kathryn M, Waters, Alaina L, Yeligar, Samantha M, Smith, Yoland, Seyfried, Nicholas T, Weinshenker, David, Hepler, John R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915580/
https://www.ncbi.nlm.nih.gov/pubmed/36778349
http://dx.doi.org/10.1101/2023.02.01.526349