Coevolution of the CDCA7-HELLS ICF-related nucleosome remodeling complex and DNA methyltransferases

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5-Methylcytosine (5mC) and DNA methyltransferases (DNMTs) are broadly conserved in eukaryotes but are also frequently lost during evolution. The mammalian SNF2 family ATPase HELLS and its plant ortholog DDM1 are critical for maintaining 5mC. Mutations in HELLS, its activator CDCA7, and the de novo D...

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Detalles Bibliográficos
Autores principales: Funabiki, Hironori, Wassing, Isabel E., Jia, Qingyuan, Luo, Ji-Dung, Carroll, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915587/
https://www.ncbi.nlm.nih.gov/pubmed/36778482
http://dx.doi.org/10.1101/2023.01.30.526367

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915587/
https://www.ncbi.nlm.nih.gov/pubmed/36778482
http://dx.doi.org/10.1101/2023.01.30.526367

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