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Structural prediction of chimeric immunogens to elicit targeted antibodies against betacoronaviruses
Betacoronaviruses pose an ongoing pandemic threat. Antigenic evolution of the SARS-CoV-2 virus has shown that much of the spontaneous antibody response is narrowly focused rather than broadly neutralizing against even SARS-CoV-2 variants, let alone future threats. One way to overcome this is by focu...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915606/ https://www.ncbi.nlm.nih.gov/pubmed/36778336 http://dx.doi.org/10.1101/2023.01.31.526494 |