Borrelia burgdorferi PlzA is a cyclic-di-GMP dependent DNA- and RNA-binding protein

The PilZ domain-containing protein, PlzA, is the only cyclic di-GMP binding protein encoded by all Lyme disease spirochetes. PlzA has been implicated in the regulation of many borrelial processes, but the effector mechanism of PlzA was not previously known. Here we report that PlzA can bind DNA and...

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Detalles Bibliográficos
Autores principales: Jusufovic, Nerina, Krusenstjerna, Andrew C., Savage, Christina R., Saylor, Timothy C., Brissette, Catherine A., Zückert, Wolfram R., Schlax, Paula J., Motaleb, Md A., Stevenson, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915621/
https://www.ncbi.nlm.nih.gov/pubmed/36778503
http://dx.doi.org/10.1101/2023.01.30.526351

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915621/
https://www.ncbi.nlm.nih.gov/pubmed/36778503
http://dx.doi.org/10.1101/2023.01.30.526351

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