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Understanding the Free Energy Landscape of Phase Separation in Lipid Bilayers using Molecular Dynamics

Liquid-liquid phase separation (LLPS) inside the cell often results in biological condensates that can critically impact cell homeostasis. Such phase separation events occur in multiple parts of cells, including the cell membranes, where the so-called “lipid raft” hypothesis posits the formation of...

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Detalles Bibliográficos
Autores principales: Poruthoor, Ashlin J., Sharma, Akshara, Grossfield, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915641/
https://www.ncbi.nlm.nih.gov/pubmed/36778479
http://dx.doi.org/10.1101/2023.01.31.526537