Perturb-tracing enables high-content screening of multiscale 3D genome regulators

Three-dimensional (3D) genome organization becomes altered during development, aging, and disease(1–23), but the factors regulating chromatin topology are incompletely understood and currently no technology can efficiently screen for new regulators of multiscale chromatin organization. Here, we deve...

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Detalles Bibliográficos
Autores principales: Cheng, Yubao, Hu, Mengwei, Yang, Bing, Jensen, Tyler B, Yang, Tianqi, Yu, Ruihuan, Ma, Zhaoxia, Radda, Jonathan S D, Jin, Shengyan, Zang, Chongzhi, Wang, Siyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915657/
https://www.ncbi.nlm.nih.gov/pubmed/36778402
http://dx.doi.org/10.1101/2023.01.31.525983

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915657/
https://www.ncbi.nlm.nih.gov/pubmed/36778402
http://dx.doi.org/10.1101/2023.01.31.525983

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