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Perturb-tracing enables high-content screening of multiscale 3D genome regulators
Three-dimensional (3D) genome organization becomes altered during development, aging, and disease(1–23), but the factors regulating chromatin topology are incompletely understood and currently no technology can efficiently screen for new regulators of multiscale chromatin organization. Here, we deve...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915657/ https://www.ncbi.nlm.nih.gov/pubmed/36778402 http://dx.doi.org/10.1101/2023.01.31.525983 |