Path integration selectively predicts midlife risk of Alzheimer’s disease

The entorhinal cortex (EC) is the first cortical region to exhibit neurodegeneration in Alzheimer’s disease (AD), associated with EC grid cell dysfunction. Given the role of grid cells in path integration, we predicted that path integration impairment would represent the first behavioural change in...

Descripción completa

Detalles Bibliográficos
Autores principales: Newton, Coco, Pope, Marianna, Rua, Catarina, Henson, Richard, Ji, Zilong, Burgess, Neil, Rodgers, Christopher T., Stangl, Matthias, Dounavi, Maria-Eleni, Castegnaro, Andrea, Koychev, Ivan, Malhotra, Paresh, Wolbers, Thomas, Ritchie, Karen, Ritchie, Craig W., O’Brien, John, Su, Li, Chan, Dennis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915680/
https://www.ncbi.nlm.nih.gov/pubmed/36778428
http://dx.doi.org/10.1101/2023.01.31.526473

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915680/
https://www.ncbi.nlm.nih.gov/pubmed/36778428
http://dx.doi.org/10.1101/2023.01.31.526473

Ejemplares similares