Cargando…

Identifying Human Specific Adverse Outcome Pathways of Per- and Polyfluoroalkyl Substances Using Liver-Chimeric Humanized Mice

BACKGROUND: Per- and polyfluoroalkyl substances (PFAS) are persistent organic pollutants with myriad adverse effects. While perfluorooctanoic acid (PFOA) and perfluorooctane sulfonic acid (PFOS) are the most common contaminants, levels of replacement PFAS, such as perfluoro-2-methyl-3-oxahexanoic ac...

Descripción completa

Detalles Bibliográficos
Autores principales: Robarts, Dakota R., Paine-Cabrera, Diego, Kotulkar, Manasi, Venneman, Kaitlyn K., Gunewardena, Sumedha, Corton, J. Christopher, Lau, Christopher, Foquet, Lander, Bial, Greg, Apte, Udayan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915685/
https://www.ncbi.nlm.nih.gov/pubmed/36778348
http://dx.doi.org/10.1101/2023.02.01.526711