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Sindbis virus is suppressed in the yellow fever mosquito Aedes aegypti by ATG-6/Beclin-1 mediated activation of autophagy

Autophagy is a critical modulator of pathogen invasion response in vertebrates and invertebrates. However, how it affects mosquito-borne viral pathogens that significantly burden public health remains underexplored. To address this gap, we use a genetic approach to activate macroautophagy/autophagy...

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Detalles Bibliográficos
Autores principales: Pujhari, Sujit, Heu, Chan C., Brustolin, Marco, Johnson, Rebecca M., Kim, Donghun, Rasgon, Jason L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915692/
https://www.ncbi.nlm.nih.gov/pubmed/36778292
http://dx.doi.org/10.1101/2023.02.02.526867