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Sindbis virus is suppressed in the yellow fever mosquito Aedes aegypti by ATG-6/Beclin-1 mediated activation of autophagy
Autophagy is a critical modulator of pathogen invasion response in vertebrates and invertebrates. However, how it affects mosquito-borne viral pathogens that significantly burden public health remains underexplored. To address this gap, we use a genetic approach to activate macroautophagy/autophagy...
Autores principales: | Pujhari, Sujit, Heu, Chan C., Brustolin, Marco, Johnson, Rebecca M., Kim, Donghun, Rasgon, Jason L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915692/ https://www.ncbi.nlm.nih.gov/pubmed/36778292 http://dx.doi.org/10.1101/2023.02.02.526867 |
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