Effect of Arylazo Sulfones on DNA: Binding, Cleavage, Photocleavage, Molecular Docking Studies and Interaction with A375 Melanoma and Non-Cancer Cells

A set of arylazo sulfones, known to undergo N–S bond cleavage upon light exposure, has been synthesized, and their activity in the dark and upon irradiation towards DNA has been investigated. Their interaction with calf-thymus DNA has been examined, and the significant affinity observed (most probab...

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Detalles Bibliográficos
Autores principales: Mikra, Chrysoula, Mitrakas, Achilleas, Ghizzani, Virginia, Katsani, Katerina R., Koffa, Maria, Koukourakis, Michael, Psomas, George, Protti, Stefano, Fagnoni, Maurizio, Fylaktakidou, Konstantina C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915714/
https://www.ncbi.nlm.nih.gov/pubmed/36768159
http://dx.doi.org/10.3390/ijms24031834

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915714/
https://www.ncbi.nlm.nih.gov/pubmed/36768159
http://dx.doi.org/10.3390/ijms24031834

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