Structure primed embedding on the transcription factor manifold enables transparent model architectures for gene regulatory network and latent activity inference

The modeling of gene regulatory networks (GRNs) is limited due to a lack of direct measurements of regulatory features in genome-wide screens. Most GRN inference methods are therefore forced to model relationships between regulatory genes and their targets with expression as a proxy for the upstream...

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Detalles Bibliográficos
Autores principales: Tjärnberg, Andreas, Beheler-Amass, Maggie, Jackson, Christopher A, Christiaen, Lionel A, Gresham, David, Bonneau, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915715/
https://www.ncbi.nlm.nih.gov/pubmed/36778259
http://dx.doi.org/10.1101/2023.02.02.526909

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915715/
https://www.ncbi.nlm.nih.gov/pubmed/36778259
http://dx.doi.org/10.1101/2023.02.02.526909

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