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A New Plasmacytoid Dendritic Cell-Based Vaccine in Combination with Anti-PD-1 Expands the Tumor-Specific CD8+ T Cells of Lung Cancer Patients

The purpose of immune checkpoint inhibitor (ICI)-based therapies is to help the patient’s immune system to combat tumors by restoring the immune response mediated by CD8+ cytotoxic T cells. Despite impressive clinical responses, most patients do not respond to ICIs. Therapeutic vaccines with autolog...

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Detalles Bibliográficos
Autores principales: Hannani, Dalil, Leplus, Estelle, Laurin, David, Caulier, Benjamin, Aspord, Caroline, Madelon, Natacha, Bourova-Flin, Ekaterina, Brambilla, Christian, Brambilla, Elisabeth, Toffart, Anne-Claire, Laulagnier, Karine, Chaperot, Laurence, Plumas, Joël
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915756/
https://www.ncbi.nlm.nih.gov/pubmed/36768214
http://dx.doi.org/10.3390/ijms24031897