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Regulation of Ferroptosis by Transcription Factor E2F1 and RB

Tumor suppressor RB binds to E2F family proteins and modulates cell cycle progression. Cyclin dependent kinases (CDK) regulate the interaction of RB/E2F by phosphorylating RB. Previously, we have revealed that CDK2, RB and E2F inhibit ferroptosis. Ferroptosis is a non-apoptotic, iron-dependent form...

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Detalles Bibliográficos
Autores principales: Kuganesan, Nishanth, Dlamini, Samkeliso, Tillekeratne, Viranga LM, Taylor, William R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915776/
https://www.ncbi.nlm.nih.gov/pubmed/36778475
http://dx.doi.org/10.21203/rs.3.rs-2493335/v1