MRBEE: A novel bias-corrected multivariable Mendelian Randomization method

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Mendelian Randomization (MR) has been widely applied to infer causality of exposures on outcomes in the genome wide association (GWAS) era. Existing approaches are often subject to biases from multiple sources including weak instruments, sample overlap, and measurement error. We introduce MRBEE, a c...

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Detalles Bibliográficos
Autores principales: Lorincz-Comi, Noah, Yang, Yihe, Li, Gen, Zhu, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915796/
https://www.ncbi.nlm.nih.gov/pubmed/36778480
http://dx.doi.org/10.21203/rs.3.rs-2464632/v1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915796/
https://www.ncbi.nlm.nih.gov/pubmed/36778480
http://dx.doi.org/10.21203/rs.3.rs-2464632/v1

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