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MRBEE: A novel bias-corrected multivariable Mendelian Randomization method
Mendelian Randomization (MR) has been widely applied to infer causality of exposures on outcomes in the genome wide association (GWAS) era. Existing approaches are often subject to biases from multiple sources including weak instruments, sample overlap, and measurement error. We introduce MRBEE, a c...
Autores principales: | Lorincz-Comi, Noah, Yang, Yihe, Li, Gen, Zhu, Xiaofeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915796/ https://www.ncbi.nlm.nih.gov/pubmed/36778480 http://dx.doi.org/10.21203/rs.3.rs-2464632/v1 |
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