Identification of Potent Zika Virus NS5 RNA-Dependent RNA Polymerase Inhibitors Combining Virtual Screening and Biological Assays

The Zika virus (ZIKV) epidemic poses a significant threat to human health globally. Thus, there is an urgent need for developing effective anti-ZIKV agents. ZIKV non-structural protein 5 RNA-dependent RNA polymerase (RdRp), a viral enzyme for viral replication, has been considered an attractive drug...

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Detalles Bibliográficos
Autores principales: Chen, Ying, Chi, Xiangyin, Zhang, Hongjuan, Zhang, Yu, Qiao, Luyao, Ding, Jinwen, Han, Yanxing, Lin, Yuan, Jiang, Jiandong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915956/
https://www.ncbi.nlm.nih.gov/pubmed/36768218
http://dx.doi.org/10.3390/ijms24031900

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915956/
https://www.ncbi.nlm.nih.gov/pubmed/36768218
http://dx.doi.org/10.3390/ijms24031900

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