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Identification of Potent Zika Virus NS5 RNA-Dependent RNA Polymerase Inhibitors Combining Virtual Screening and Biological Assays
The Zika virus (ZIKV) epidemic poses a significant threat to human health globally. Thus, there is an urgent need for developing effective anti-ZIKV agents. ZIKV non-structural protein 5 RNA-dependent RNA polymerase (RdRp), a viral enzyme for viral replication, has been considered an attractive drug...
Autores principales: | Chen, Ying, Chi, Xiangyin, Zhang, Hongjuan, Zhang, Yu, Qiao, Luyao, Ding, Jinwen, Han, Yanxing, Lin, Yuan, Jiang, Jiandong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915956/ https://www.ncbi.nlm.nih.gov/pubmed/36768218 http://dx.doi.org/10.3390/ijms24031900 |
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