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Early Gastric Cancer: Update on Prevention, Diagnosis and Treatment
Gastric cancer (GC) is a relevant public health issue as its incidence and mortality rates are growing worldwide. There are recognized carcinogen agents, such as obesity, tobacco, meat, alcohol consumption and some dietary protective factors. Strategies of early diagnosis through population-based su...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9916026/ https://www.ncbi.nlm.nih.gov/pubmed/36767516 http://dx.doi.org/10.3390/ijerph20032149 |
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author | Conti, Clara Benedetta Agnesi, Stefano Scaravaglio, Miki Masseria, Pietro Dinelli, Marco Emilio Oldani, Massimo Uggeri, Fabio |
author_facet | Conti, Clara Benedetta Agnesi, Stefano Scaravaglio, Miki Masseria, Pietro Dinelli, Marco Emilio Oldani, Massimo Uggeri, Fabio |
author_sort | Conti, Clara Benedetta |
collection | PubMed |
description | Gastric cancer (GC) is a relevant public health issue as its incidence and mortality rates are growing worldwide. There are recognized carcinogen agents, such as obesity, tobacco, meat, alcohol consumption and some dietary protective factors. Strategies of early diagnosis through population-based surveillance programs have been demonstrated to be effective in lowering the morbidity and mortality related to GC in some countries. Indeed, the detection of early lesions is very important in order to offer minimally invasive treatments. Endoscopic resection is the gold standard for lesions with a low risk of lymph node metastasis, whereas surgical mini-invasive approaches can be considered in early lesions when endoscopy is not curative. This review outlines the role of lifestyle and prevention strategies for GC, in order to reduce the patients’ risk factors, implement the surveillance of precancerous conditions and, therefore, improve the diagnosis of early lesions. Furthermore, we summarize the available treatments for early gastric cancer. |
format | Online Article Text |
id | pubmed-9916026 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-99160262023-02-11 Early Gastric Cancer: Update on Prevention, Diagnosis and Treatment Conti, Clara Benedetta Agnesi, Stefano Scaravaglio, Miki Masseria, Pietro Dinelli, Marco Emilio Oldani, Massimo Uggeri, Fabio Int J Environ Res Public Health Review Gastric cancer (GC) is a relevant public health issue as its incidence and mortality rates are growing worldwide. There are recognized carcinogen agents, such as obesity, tobacco, meat, alcohol consumption and some dietary protective factors. Strategies of early diagnosis through population-based surveillance programs have been demonstrated to be effective in lowering the morbidity and mortality related to GC in some countries. Indeed, the detection of early lesions is very important in order to offer minimally invasive treatments. Endoscopic resection is the gold standard for lesions with a low risk of lymph node metastasis, whereas surgical mini-invasive approaches can be considered in early lesions when endoscopy is not curative. This review outlines the role of lifestyle and prevention strategies for GC, in order to reduce the patients’ risk factors, implement the surveillance of precancerous conditions and, therefore, improve the diagnosis of early lesions. Furthermore, we summarize the available treatments for early gastric cancer. MDPI 2023-01-25 /pmc/articles/PMC9916026/ /pubmed/36767516 http://dx.doi.org/10.3390/ijerph20032149 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Conti, Clara Benedetta Agnesi, Stefano Scaravaglio, Miki Masseria, Pietro Dinelli, Marco Emilio Oldani, Massimo Uggeri, Fabio Early Gastric Cancer: Update on Prevention, Diagnosis and Treatment |
title | Early Gastric Cancer: Update on Prevention, Diagnosis and Treatment |
title_full | Early Gastric Cancer: Update on Prevention, Diagnosis and Treatment |
title_fullStr | Early Gastric Cancer: Update on Prevention, Diagnosis and Treatment |
title_full_unstemmed | Early Gastric Cancer: Update on Prevention, Diagnosis and Treatment |
title_short | Early Gastric Cancer: Update on Prevention, Diagnosis and Treatment |
title_sort | early gastric cancer: update on prevention, diagnosis and treatment |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9916026/ https://www.ncbi.nlm.nih.gov/pubmed/36767516 http://dx.doi.org/10.3390/ijerph20032149 |
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