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Early Gastric Cancer: Update on Prevention, Diagnosis and Treatment

Gastric cancer (GC) is a relevant public health issue as its incidence and mortality rates are growing worldwide. There are recognized carcinogen agents, such as obesity, tobacco, meat, alcohol consumption and some dietary protective factors. Strategies of early diagnosis through population-based su...

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Autores principales: Conti, Clara Benedetta, Agnesi, Stefano, Scaravaglio, Miki, Masseria, Pietro, Dinelli, Marco Emilio, Oldani, Massimo, Uggeri, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9916026/
https://www.ncbi.nlm.nih.gov/pubmed/36767516
http://dx.doi.org/10.3390/ijerph20032149
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author Conti, Clara Benedetta
Agnesi, Stefano
Scaravaglio, Miki
Masseria, Pietro
Dinelli, Marco Emilio
Oldani, Massimo
Uggeri, Fabio
author_facet Conti, Clara Benedetta
Agnesi, Stefano
Scaravaglio, Miki
Masseria, Pietro
Dinelli, Marco Emilio
Oldani, Massimo
Uggeri, Fabio
author_sort Conti, Clara Benedetta
collection PubMed
description Gastric cancer (GC) is a relevant public health issue as its incidence and mortality rates are growing worldwide. There are recognized carcinogen agents, such as obesity, tobacco, meat, alcohol consumption and some dietary protective factors. Strategies of early diagnosis through population-based surveillance programs have been demonstrated to be effective in lowering the morbidity and mortality related to GC in some countries. Indeed, the detection of early lesions is very important in order to offer minimally invasive treatments. Endoscopic resection is the gold standard for lesions with a low risk of lymph node metastasis, whereas surgical mini-invasive approaches can be considered in early lesions when endoscopy is not curative. This review outlines the role of lifestyle and prevention strategies for GC, in order to reduce the patients’ risk factors, implement the surveillance of precancerous conditions and, therefore, improve the diagnosis of early lesions. Furthermore, we summarize the available treatments for early gastric cancer.
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spelling pubmed-99160262023-02-11 Early Gastric Cancer: Update on Prevention, Diagnosis and Treatment Conti, Clara Benedetta Agnesi, Stefano Scaravaglio, Miki Masseria, Pietro Dinelli, Marco Emilio Oldani, Massimo Uggeri, Fabio Int J Environ Res Public Health Review Gastric cancer (GC) is a relevant public health issue as its incidence and mortality rates are growing worldwide. There are recognized carcinogen agents, such as obesity, tobacco, meat, alcohol consumption and some dietary protective factors. Strategies of early diagnosis through population-based surveillance programs have been demonstrated to be effective in lowering the morbidity and mortality related to GC in some countries. Indeed, the detection of early lesions is very important in order to offer minimally invasive treatments. Endoscopic resection is the gold standard for lesions with a low risk of lymph node metastasis, whereas surgical mini-invasive approaches can be considered in early lesions when endoscopy is not curative. This review outlines the role of lifestyle and prevention strategies for GC, in order to reduce the patients’ risk factors, implement the surveillance of precancerous conditions and, therefore, improve the diagnosis of early lesions. Furthermore, we summarize the available treatments for early gastric cancer. MDPI 2023-01-25 /pmc/articles/PMC9916026/ /pubmed/36767516 http://dx.doi.org/10.3390/ijerph20032149 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Conti, Clara Benedetta
Agnesi, Stefano
Scaravaglio, Miki
Masseria, Pietro
Dinelli, Marco Emilio
Oldani, Massimo
Uggeri, Fabio
Early Gastric Cancer: Update on Prevention, Diagnosis and Treatment
title Early Gastric Cancer: Update on Prevention, Diagnosis and Treatment
title_full Early Gastric Cancer: Update on Prevention, Diagnosis and Treatment
title_fullStr Early Gastric Cancer: Update on Prevention, Diagnosis and Treatment
title_full_unstemmed Early Gastric Cancer: Update on Prevention, Diagnosis and Treatment
title_short Early Gastric Cancer: Update on Prevention, Diagnosis and Treatment
title_sort early gastric cancer: update on prevention, diagnosis and treatment
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9916026/
https://www.ncbi.nlm.nih.gov/pubmed/36767516
http://dx.doi.org/10.3390/ijerph20032149
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