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Canagliflozin ameliorates the development of NAFLD by preventing NLRP3-mediated pyroptosis through FGF21-ERK1/2 pathway

Recent studies have suggested that sodium-glucose co-transporter2 inhibitors go beyond their glycemic advantages to ameliorate the development of NAFLD. However, little research has been done on the underlying mechanisms. Here, we took deep insight into the effect of canagliflozin (CANA), one of the...

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Detalles Bibliográficos
Autores principales: Huang, Shaohan, Wu, Beibei, He, Yingzi, Qiu, Ruojun, Yang, Tian, Wang, Shuo, Lei, Yongzhen, Li, Hong, Zheng, Fenping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9916118/
https://www.ncbi.nlm.nih.gov/pubmed/36757426
http://dx.doi.org/10.1097/HC9.0000000000000045