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Gliflozins Have an Anti-Inflammatory Effect on Renal Proximal Tubular Epithelial Cells in a Diabetic and Inflammatory Microenvironment In Vitro

Inflammation is intimately involved in the pathogenesis of diabetic kidney disease. Inhibition of SGLT-2 by a specific class of drugs, gliflozins, has been shown to reduce inflammation and attenuate the progression of diabetic nephropathy, in addition to its main effect of inhibiting renal glucose r...

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Detalles Bibliográficos
Autores principales: Koch, Benjamin, Fuhrmann, Dominik C., Schubert, Ralf, Geiger, Helmut, Speer, Thimoteus, Baer, Patrick C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9916320/
https://www.ncbi.nlm.nih.gov/pubmed/36768138
http://dx.doi.org/10.3390/ijms24031811