Design, Synthesis and Pharmacological Evaluation of New Quinoline-Based Panx-1 Channel Blockers

Pannexins are an interesting new target in medicinal chemistry, as they are involved in many pathologies such as epilepsy, ischemic stroke, cancer and Parkinson’s disease, as well as in neuropathic pain. They are a family of membrane channel proteins consisting of three members, Panx-1, Panx-2 and P...

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Detalles Bibliográficos
Autores principales: Crocetti, Letizia, Giovannoni, Maria Paola, Guerrini, Gabriella, Lamanna, Silvia, Melani, Fabrizio, Bartolucci, Gianluca, Pallecchi, Marco, Paoli, Paola, Lippi, Martina, Wang, Junjie, Dahl, Gerhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9916356/
https://www.ncbi.nlm.nih.gov/pubmed/36768344
http://dx.doi.org/10.3390/ijms24032022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9916356/
https://www.ncbi.nlm.nih.gov/pubmed/36768344
http://dx.doi.org/10.3390/ijms24032022

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