DDC-Promoter-Driven Chemogenetic Activation of SNpc Dopaminergic Neurons Alleviates Parkinsonian Motor Symptoms

Parkinson’s disease (PD) is a neurodegenerative disorder with typical motor symptoms. Recent studies have suggested that excessive GABA from reactive astrocytes tonically inhibits dopaminergic neurons and reduces the expression of tyrosine hydroxylase (TH), the key dopamine-synthesizing enzyme, in t...

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Detalles Bibliográficos
Autores principales: Seo, Dong-Chan, Ju, Yeon Ha, Seo, Jin-Ju, Oh, Soo-Jin, Lee, C. Justin, Lee, Seung Eun, Nam, Min-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9916413/
https://www.ncbi.nlm.nih.gov/pubmed/36768816
http://dx.doi.org/10.3390/ijms24032491

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9916413/
https://www.ncbi.nlm.nih.gov/pubmed/36768816
http://dx.doi.org/10.3390/ijms24032491

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