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The Immunogenicity of DENV1–4 ED3s Strongly Differ despite Their Almost Identical Three-Dimensional Structures and High Sequence Similarities

The development of a dengue (DENV) vaccine remains challenging due to the heteroserotypic infection, which can result in a potentially deadly hemorrhagic fever or dengue shock syndrome, and only a tetravalent vaccine can overcome this issue. Here, we report the immunogenicity of DENV envelope protei...

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Detalles Bibliográficos
Autores principales: Islam, Md. Din, Sharmin, Tahmina, Tipo, Imrul Hasan, Saha, Antara, Yesmin, Sanjida, Roy, Moushumi Ghosh, Brindha, Subbaian, Kuroda, Yutaka, Islam, M. Monirul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9916489/
https://www.ncbi.nlm.nih.gov/pubmed/36768719
http://dx.doi.org/10.3390/ijms24032393