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p27(Kip1) Deficiency Impairs Brown Adipose Tissue Function Favouring Fat Accumulation in Mice

The aim of this work was to investigate the effect of the whole-body deletion of p27 on the activity of brown adipose tissue and the susceptibility to develop obesity and glucose homeostasis disturbances in mice, especially when subjected to a high fat diet. p27 knockout (p27(−/−)) and wild type (WT...

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Detalles Bibliográficos
Autores principales: Colon-Mesa, Ignacio, Sainz, Neira, Corrales, Patricia, Collantes, María, Kaldis, Philipp, Martinez, José Alfredo, Medina-Gómez, Gema, Moreno-Aliaga, María Jesús, Escoté, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9916555/
https://www.ncbi.nlm.nih.gov/pubmed/36768986
http://dx.doi.org/10.3390/ijms24032664