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Expression, purification, and characterisation of the p53 binding domain of Retinoblastoma binding protein 6 (RBBP6)

RBBP6 is a 250 kDa eukaryotic protein known to be a negative regulator of p53 and essential for embryonic development. Furthermore, RBBP6 is a critical element in carcinogenesis and has been identified as a potential biomarker for certain cancers. RBBP6’s ability to interact with p53 and cause its d...

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Detalles Bibliográficos
Autores principales: Russell, Bonnie L., Ntwasa, Monde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9916574/
https://www.ncbi.nlm.nih.gov/pubmed/36763571
http://dx.doi.org/10.1371/journal.pone.0277478