Learning high-order interactions for polygenic risk prediction

Within the framework of precision medicine, the stratification of individual genetic susceptibility based on inherited DNA variation has paramount relevance. However, one of the most relevant pitfalls of traditional Polygenic Risk Scores (PRS) approaches is their inability to model complex high-orde...

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Detalles Bibliográficos
Autores principales: Massi, Michela C., Franco, Nicola R., Manzoni, Andrea, Paganoni, Anna Maria, Park, Hanla A., Hoffmeister, Michael, Brenner, Hermann, Chang-Claude, Jenny, Ieva, Francesca, Zunino, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9916647/
https://www.ncbi.nlm.nih.gov/pubmed/36763605
http://dx.doi.org/10.1371/journal.pone.0281618

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9916647/
https://www.ncbi.nlm.nih.gov/pubmed/36763605
http://dx.doi.org/10.1371/journal.pone.0281618

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