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Discovery of Small Molecule COX-1 and Akt Inhibitors as Anti-NSCLC Agents Endowed with Anti-Inflammatory Action

Targeted therapies have come into prominence in the ongoing battle against non-small cell lung cancer (NSCLC) because of the shortcomings of traditional chemotherapy. In this context, indole-based small molecules, which were synthesized efficiently, were subjected to an in vitro colorimetric assay t...

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Detalles Bibliográficos
Autores principales: Altıntop, Mehlika Dilek, Akalın Çiftçi, Gülşen, Yılmaz Savaş, Nalan, Ertorun, İpek, Can, Betül, Sever, Belgin, Temel, Halide Edip, Alataş, Özkan, Özdemir, Ahmet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9916685/
https://www.ncbi.nlm.nih.gov/pubmed/36768971
http://dx.doi.org/10.3390/ijms24032648