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Recombinant Peptide Production Softens Escherichia coli Cells and Increases Their Size during C-Limited Fed-Batch Cultivation

Stress-associated changes in the mechanical properties at the single-cell level of Escherichia coli (E. coli) cultures in bioreactors are still poorly investigated. In our study, we compared peptide-producing and non-producing BL21(DE3) cells in a fed-batch cultivation with tightly controlled proces...

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Detalles Bibliográficos
Autores principales: Weber, Andreas, Gibisch, Martin, Tyrakowski, Daniel, Cserjan-Puschmann, Monika, Toca-Herrera, José L., Striedner, Gerald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9916741/
https://www.ncbi.nlm.nih.gov/pubmed/36768962
http://dx.doi.org/10.3390/ijms24032641