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Comparative Analysis of Normoxia- and Hypoxia-Modified Extracellular Vesicle Therapy in Function, Perfusion, and Collateralization in Chronically Ischemic Myocardium

We have previously shown that normoxia serum-starved extracellular vesicle (EV) therapy improves myocardial function, perfusion, and angiogenesis in a swine model of chronic myocardial ischemia. Hypoxia-modified EVs have increased abundance of anti-oxidant, pro-angiogenic, and pro-survival proteins....

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Detalles Bibliográficos
Autores principales: Sabe, Sharif A., Xu, Cynthia M., Potz, Brittany A., Malhotra, Akshay, Sabra, Mohamed, Harris, Dwight D., Broadwin, Mark, Abid, M. Ruhul, Sellke, Frank W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9916784/
https://www.ncbi.nlm.nih.gov/pubmed/36768399
http://dx.doi.org/10.3390/ijms24032076