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Comparative Analysis of Normoxia- and Hypoxia-Modified Extracellular Vesicle Therapy in Function, Perfusion, and Collateralization in Chronically Ischemic Myocardium
We have previously shown that normoxia serum-starved extracellular vesicle (EV) therapy improves myocardial function, perfusion, and angiogenesis in a swine model of chronic myocardial ischemia. Hypoxia-modified EVs have increased abundance of anti-oxidant, pro-angiogenic, and pro-survival proteins....
Autores principales: | Sabe, Sharif A., Xu, Cynthia M., Potz, Brittany A., Malhotra, Akshay, Sabra, Mohamed, Harris, Dwight D., Broadwin, Mark, Abid, M. Ruhul, Sellke, Frank W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9916784/ https://www.ncbi.nlm.nih.gov/pubmed/36768399 http://dx.doi.org/10.3390/ijms24032076 |
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