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Tachykinin Receptor-Selectivity of the Potential Glioblastoma-Targeted Therapy, DOTA-[Thi(8),Met(O(2))(11)]-Substance P

Radiopharmaceutical development hinges on the affinity and selectivity of the biological component for the intended target. An analogue of the neuropeptide Substance P (SP), 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid-[Thi(8),Met(O(2))(11)]-SP (DOTA-[Thi(8),Met(O(2))(11)]SP), in the the...

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Detalles Bibliográficos
Autores principales: Suthiram, Janine, Pieters, Ané, Mohamed Moosa, Zulfiah, Zeevaart, Jan Rijn, Sathekge, Mike M., Ebenhan, Thomas, Anderson, Ross C., Newton, Claire L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9916806/
https://www.ncbi.nlm.nih.gov/pubmed/36768456
http://dx.doi.org/10.3390/ijms24032134