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Cytotoxic Effects of Darinaparsin, a Novel Organic Arsenical, against Human Leukemia Cells

To explore the molecular mechanisms of action underlying the antileukemia activities of darinaparsin, an organic arsenical approved for the treatment of peripheral T–cell lymphoma in Japan, cytotoxicity of darinaparsin was evaluated in leukemia cell lines NB4, U-937, MOLT-4 and HL-60. Darinaparsin w...

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Detalles Bibliográficos
Autores principales: Yuan, Bo, Kikuchi, Hidetomo, Li, Jingmei, Kawabata, Atsushi, Yao, Kozo, Takagi, Norio, Okazaki, Mari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9916914/
https://www.ncbi.nlm.nih.gov/pubmed/36768603
http://dx.doi.org/10.3390/ijms24032282