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Interaction of Tryptophan- and Arginine-Rich Antimicrobial Peptide with E. coli Outer Membrane—A Molecular Simulation Approach

A short antimicrobial peptide (AMP), rich in tryptophan and arginine (P6—HRWWRWWRR-NH2), was used in molecular dynamics (MD) simulations to investigate the interaction between AMPs and lipopolysaccharides (LPS) from two E. coli outer membrane (OM) membrane models. The OM of Gram-negative bacteria is...

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Detalles Bibliográficos
Autores principales: Necula, George, Bacalum, Mihaela, Radu, Mihai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9916935/
https://www.ncbi.nlm.nih.gov/pubmed/36768325
http://dx.doi.org/10.3390/ijms24032005