Kappa Opioid Receptors Reduce Serotonin Uptake and Escitalopram Efficacy in the Mouse Substantia Nigra Pars Reticulata

The serotonin and kappa opioid receptor (KOR) systems are strongly implicated in disorders of negative affect, such as anxiety and depression. KORs expressed on axon terminals inhibit the release of neurotransmitters, including serotonin. The substantia nigra pars reticulata (SNr) is involved in reg...

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Detalles Bibliográficos
Autores principales: West, Alyssa M., Holleran, Katherine M., Jones, Sara R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9916942/
https://www.ncbi.nlm.nih.gov/pubmed/36768403
http://dx.doi.org/10.3390/ijms24032080

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9916942/
https://www.ncbi.nlm.nih.gov/pubmed/36768403
http://dx.doi.org/10.3390/ijms24032080

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