Cytotoxicity of Isoxazole Curcumin Analogs on Chronic Myeloid Leukemia-Derived K562 Cell Lines Sensitive and Resistant to Imatinib

Despite curcumin (CUR) inhibiting cell proliferation in vitro by activating apoptotic cell death, its use in pharmacological therapy is hampered by poor solubility, low stability in biological fluids, and rapid removal from the body. Therefore, CUR-derivatives with better biological and chemical–phy...

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Detalles Bibliográficos
Autores principales: Feriotto, Giordana, Marchetti, Paolo, Rondanin, Riccardo, Tagliati, Federico, Aguzzi, Serena, Beninati, Simone, Casciano, Fabio, Tabolacci, Claudio, Mischiati, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9916957/
https://www.ncbi.nlm.nih.gov/pubmed/36768681
http://dx.doi.org/10.3390/ijms24032356

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9916957/
https://www.ncbi.nlm.nih.gov/pubmed/36768681
http://dx.doi.org/10.3390/ijms24032356

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